ENPEP anticorps

N° du produit ABIN6989600

L’anticorps Lapin Monoclonal anti-ENPEP a été validé pour WB, IHC et IHC (p). Il convient pour détecter ENPEP dans des échantillons de Humain.

Aperçu rapide pour ENPEP anticorps (ABIN6989600)

Antigène: ENPEP (Glutamyl Aminopeptidase (Aminopeptidase A) (ENPEP))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp ENPEP est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 11B3

Détail du produit anti-ENPEP anticorps

Réactivité croisée: Humain

Purification: Purified by Protein A.

Immunogène: Synthetic Peptide within Human AP-A.

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC()

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur ENPEP

Antigène: ENPEP (Glutamyl Aminopeptidase (Aminopeptidase A) (ENPEP))

Autre désignation: AP-A

Sujet:

Synonyms: Aminopeptidase A antibody, AMPE_HUMAN antibody, AP-A antibody, APA antibody, bp-1 antibody, bp1 antibody, CD249 antibody, Differentiation antigen gp160 antibody, EAP antibody, Enpep antibody, Glutamyl aminopeptidase (aminopeptidase A) antibody, Glutamyl aminopeptidase antibody, Gp160 antibody, Ly51 antibody

Background: Aminopeptidase A, also designated APA, gp160 human kidney differentiation antigen, glutamyl aminopeptidase, or enpep, is a differentiation-related kidney glycoprotein. As a cell surface, zinc-dependent metalloprotease, Aminopepti-dase A specifically cleaves amino-terminal acidic residues from peptide substrates such as Angiotensin II. APA is expressed on the surface of epithelial cells of the glomerulus and proximal tubule cells of the human nephron, where it may mediate the constitutive trafficking of Glut4-containing vesicles. These Glut4-containing vesicles are tissue-specific secretory-like microsomal structures that mediate insulin-dependent translocation of GLUT4 to the cell surface in fat and muscle cells. Mutations in the gp160/APA gene, including loss of protein expression or enzymatic activity, occur in 20 % of primary clear cell renal carcinomas.

ID gène: 2028

UniProt: Q07075

Pathways: Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones